Summary

RWE was believed to advance RWD and its benefits. In reality, there are multiple barriers. Policies were established to overcome these barriers. The following table summarizes them:

Barrier	Approach	Policies
Data unrelated to compensation or reimbursement is poorly recorded	Improve capture at data source	Provide compensation for physicians and health care organizations, such as providing CMS Invest in AI that helps data capture
EHR does not provide complete, longitudinal data for individuals	Enable access to longitudinal whole-person data	Allow health data exchange by modifying TEFCA Implement a national all-payer claims database Invest in organizations that can link data
Regulations	Improve regulatory practices	Train FDA reviewers and inspectors Fund regulatory research such as application of AI in regulation